Table 1.
Metabolite changes in mouse urine induced by T. brucei brucei infection
| Metabolites* | δ, ppm | Day 1R2 = 0.06Q2 = 0.78 | Day 7R2 = 0.88Q2 = 0.73 | Day 14R2 = 0.94Q2 = 0.87 | Day 21R2 = 0.94Q2 = 0.87 | Day 28R2 = 0.90Q2 = 0.86 | Day 33R2 = 0.91Q2 = 0.78 |
|---|---|---|---|---|---|---|---|
| 3-Carboxy-2-methyl-3-oxopropanamine (3) | 1.08 | — | — | +0.71 | +0.75 | +0.87 | +0.81 |
| 3-Methyl-2-oxovalerate (2) | 1.11 | — | +0.50 | +0.72 | +0.84 | +0.74 | +0.77 |
| 2-Oxoisovalerate (4) | 1.14 | — | — | +0.59 | +0.69 | — | — |
| D-3-hydroxybutyrate (5) | 1.20 | — | — | — | +0.74 | +0.75 | +0.75 |
| Lactate (21) | 1.33 | — | — | — | +0.66 | +0.65 | +0.68 |
| Methylcrotonic acid (24) | 1.70 | — | −0.57 | −0.48 | −0.54 | −0.63 | — |
| Trimethylamine (10) | 2.89 | — | +0.49 | +0.62 | +0.51 | +0.51 | — |
| Tryptophan (19) | 7.30 | — | +0.64 | +0.78 | +0.78 | +0.84 | +0.74 |
| 4-Hydroxyphenylacetic acid (22) | 7.14 | — | +0.64 | +0.73 | +0.73 | +0.72 | +0.82 |
| Hippurate (20) | 7.83 | — | −0.66 | −0.59 | −0.71 | −0.70 | −0.66 |