Table 1.
Parameters for Assessing Quality of 500K Data Generated from wgaDNA
QC parameter |
||||||
---|---|---|---|---|---|---|
MCR |
MDR |
|||||
Sample | Storage time | Date of collection | NspI | StyI | NspI | StyI |
109022 serum | Recent | 11/02/2006 | 73.6 | 71.9 | 92.3 | 91.3 |
109023 serum | Recent | 04/17/2007 | 76.8 | 79.2 | 94.6 | 96.0 |
109025 serum | Recent | 04/17/2007 | 72.0 | 75.2 | 91.2 | 92.7 |
0270 plasma | ∼3 years | 01/12/2004 | 90.2 | 82.5 | 98.4 | 95.3 |
0271 plasma | ∼3 years | 01/12/2004 | 93.1 | 92.5 | 98.8 | 98.2 |
0905 serum | ∼10 years | 02/08/1997 | 63.5 | 68.6 | 88.5 | 93.0 |
8773 serum | ∼10 years | 03/05/1997 | 79.3 | 81.7 | 96.5 | 97.4 |
0625 serum | ∼20 years | 09/17/1988 | 85.9 | 92.6 | 96.7 | 98.8 |
0531 plasma | ∼20 years–TR | 04/04/1987 | 19.9 | 38.1 | 31.4 | 49.2 |
1166 plasma | ∼20 years–TR | 04/01/1987 | 53.2 | 58.7 | 66.5 | 70.6 |
109023 serum | Recent–5X | 04/17/2007 | 34.6 | 38.1 | 44.6 | 49.2 |
109025 serum | Recent–5X | 04/17/2007 | 57.3 | 58.7 | 74.2 | 70.6 |
From the dynamic mapping algorithm report in GTYPE 4.0. ∼20 years—TR, archived samples that were thawed and refrozen for other purposes at least once over time; recent–5X, samples experimentally thawed and refrozen five times to simulate heavy sample usage. NspI arrays contain 262,264 SNPs, StyI arrays contain 238,304 SNPs.