Table 2.
Cardiac-Infiltrating Leukocyte Populations in EAM in IL-13 KO Mice, Expressed as Absolute Numbers
| Population (103 cells) | KO | WT | P |
|---|---|---|---|
| CD8α+ T cells | 6.3 ± 5.0 | 1.1 ± 1.2 | 0.035 |
| CD4+ T cells | 18.4 ± 15.0 | 3.1 ± 3.5 | 0.036 |
| CD19+Mac3− B cells | 17.3 ± 10.3 | 4.5 ± 5.0 | 0.024 |
| F4/80+CD11c− macrophages | 15.8 ± 12.7 | 4.7 ± 3.3 | 0.066 |
| CD11chi dendritic cells | 36.7 ± 37.5 | 9.0 ± 12.7 | 0.122 |
| CD117+FcεRIα+ mast cells | 15.7 ± 14.3 | 3.8 ± 4.2 | 0.082 |
| CXCR2+Gr1+ neutrophils | 8.4 ± 9.7 | 2.1 ± 2.8 | 0.160 |
| DX5+TCRβ− NK cells | 9.7 ± 8.5 | 1.0 ± 0.8 | 0.033 |
| DX5+TCRβ+ NKT cells | 1.9 ± 1.8 | 0.24 ± 0.16 | 0.052 |
Absolute values were calculated by multiplying percent CD45+ values (Table 1) by enumerative cell counts of viable, noncardiomyocyte cells by Trypan Blue exclusion hemocytometry. Numbers represent mean ± SD. Statistics are by two-tailed Student’s t-test.