Table 1.
The Cross-Species Conserved 166-Gene Signature: Up-Regulated Genes
| Mouse
|
Human
|
||||
|---|---|---|---|---|---|
| Probe ID | Unigene* | Gene symbol | Unigene† | Gene symbol | Gene description |
| 1448213_at | Mm.248360 | Anxa1 | Hs.494173 | ANXA1 | Annexin A1 |
| 1424460_s_at | Mm.284649 | Aytl2 | Hs.368853 | AYTL2 | Acyltransferase like 2 |
| 1424278_a_at | Mm.8552 | Birc5 | Hs.514527 | BIRC5 | Baculoviral IAP repeat-containing 5 (survivin) |
| 1416815_s_at | Mm.927 | Bub3 | Hs.418533 | BUB3 | BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) |
| 1455356_at | Mm.36834 | Camsap1 | Hs.522493 | CAMSAP1 | Calmodulin-regulated spectrin-associated protein 1 |
| 1416884_at | Mm.280968 | Cbx3 | Hs.381189 | CBX3 | Chromobox homolog 3 (HP1 gamma homolog, Drosophila) |
| 1425616_a_at | Mm.36697 | Ccdc23 | Hs.113919 | CCDC23 | Coiled-coil domain containing 23 |
| 1427031_s_at | Mm.24035 | Ccdc52 | Hs.477144 | CCDC52 | Coiled-coil domain containing 52 |
| 1417911_at | Mm.4189 | Ccna2 | Hs.58974 | CCNA2 | Cyclin A2 |
| 1417419_at | Mm.273049 | Ccnd1 | Hs.523852 | CCND1 | Cyclin D1 |
| 1438560_x_at | Mm.296985 | Cct4 | Hs.421509 | CCT4 | Chaperonin containing TCP1, subunit 4 (delta) |
| 1417258_at | Mm.282158 | Cct5 | Hs.1600 | CCT5 | Chaperonin containing TCP1, subunit 5 (epsilon) |
| 1423760_at | Mm.423621 | Cd44 | Hs.502328 | CD44 | CD44 molecule (Indian blood group) |
| 1452242_at | Mm.9916 | Cep55 | Hs.14559 | CEP55 | Centrosomal protein 55 kDa |
| 1417457_at | Mm.222228 | Cks2 | Hs.83758 | CKS2 | CDC28 protein kinase regulatory subunit 2 |
| 1449300_at | Mm.200327 | Cttnbp2 nl | Hs.485899 | CTTNBP2NL | CTTNBP2 N-terminal like |
| 1454268_a_at | Mm.271671 | Cyba | Hs.513803 | CYBA | Cytochrome b-245, alpha polypeptide |
| 1419275_at | Mm.148693 | Dazap1 | Hs.222510 | DAZAP1 | DAZ associated protein 1 |
| 1424198_at | Mm.68971 | Dlg5 | Hs.500245 | DLG5 | Discs, large homolog 5 (Drosophila) |
| 1435122_x_at | Mm.128580 | Dnmt1 | Hs.202672 | DNMT1 | DNA (cytosine-5-)-methyltransferase 1 |
| 1452052_s_at | Mm.27695 | Eif3s1 | Hs.404056 | EIF3S1 | Eukaryotic translation initiation factor 3, subunit 1 alpha |
| 1426674_at | Mm.21671 | Eif3s9 | Hs.371001 | EIF3S9 | Eukaryotic translation initiation factor 3, subunit 9 eta |
| 1448797_at | Mm.4454 | Elk3 | Hs.591015 | ELK3 | ETS-domain protein (SRF accessory protein 2) |
| 1437211_x_at | Mm.427018 | Elovl5 | Hs.520189 | ELOVL5 | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) |
| 1420965_a_at | Mm.241073 | Enc1 | Hs.104925 | ENC1 | Ectodermal-neural cortex (with BTB-like domain) |
| 1451550_at | Mm.6972 | Ephb3 | Hs.2913 | EPHB3 | EPH receptor B3 |
| 1417301_at | Mm.4769 | Fzd6 | Hs.591863 | FZD6 | Frizzled homolog 6 (Drosophila) |
| 1419595_a_at | Mm.20461 | Ggh | Hs.78619 | GGH | Gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
| 1419205_x_at | Mm.46029 | Gpatc4 | Hs.193832 | GPATC4 | G patch domain containing 4 |
| 1433736_at | Mm.248353 | Hcfc1 | Hs.83634 | HCFC1 | Host cell factor C1 (VP16-accessory protein) |
| 1423051_at | Mm.426956 | Hnrpu | Hs.166463 | HNRPU | Heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
| 1426705_s_at | Mm.21118 | Iars | Hs.445403 | IARS | Isoleucine-tRNA synthetase |
| 1422546_at | Mm.440026 | Ilf3 | Hs.465885 | ILF3 | Interleukin enhancer binding factor 3 |
| 1456097_a_at | Mm.257094 | Itgb3bp | Hs.166539 | ITGB3BP | Integrin beta 3 binding protein (beta3-endonexin) |
| 1421344_a_at | Mm.100253 | Jub | Hs.655832 | JUB | ajuba homolog (Xenopus laevis) |
| 1452118_at | Mm.102761 | 2600005C20Rik | Hs.129621 | KIAA0179 | KIAA0179 |
| 1427080_at | Mm.29068 | 2610036D13Rik | Hs.370118 | KIAA0406 | KIAA0406 |
| 1448169_at | Mm.22479 | Krt18 | Hs.406013 | KRT18 | Keratin 18 |
| 1416621_at | Mm.285453 | Llgl1 | Hs.513983 | LLGL1 | Lethal giant larvae homolog 1 (Drosophila) |
| 1434210_s_at | Mm.245210 | Lrig1 | Hs.518055 | LRIG1 | Leucine-rich repeats and immunoglobulin-like domains 1 |
| 1417511_at | Mm.28560 | Lyar | Hs.425427 | LYAR | Hypothetical protein FLJ20425 |
| 1439426_x_at | Mm.177539 | Lzp-s | Hs.524579 | LYZ | Lysozyme (renal amyloidosis) |
| 1455941_s_at | Mm.325746 | Map2k5 | Hs.114198 | MAP2K5 | Mitogen-activated protein kinase kinase 5 |
| 1437226_x_at | Mm.424974 | Marcksl1 | Hs.75061 | MARCKSL1 | MARCKS-like 1 |
| 1439081_at | Mm.122725 | Mgea5 | Hs.500842 | MGEA5 | Meningioma expressed antigen 5 (hyaluronidase) |
| 1424001_at | Mm.280311 | Mki67ip | Hs.367842 | MKI67IP | MKI67 (FHA domain) interacting nucleolar phosphoprotein |
| 1449478_at | Mm.4825 | Mmp7 | Hs.2256 | MMP7 | Matrix metallopeptidase 7 (matrilysin, uterine) |
| 1455129_at | Mm.130883 | Mtdh | Hs.377155 | MTDH | Metadherin |
| 1419254_at | Mm.443 | Mthfd2 | Hs.469030 | MTHFD2 | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| 1452778_x_at | Mm.290407 | Nap1l1 | Hs.524599 | NAP1L1 | Nucleosome assembly protein 1-like 1 |
| 1423046_s_at | Mm.290027 | Ncbp2 | Hs.591671 | NCBP2 | Nuclear cap binding protein subunit 2 |
| 1455035_s_at | Mm.29363 | Nol5a | Hs.376064 | NOL5A | Nucleolar protein 5A (56 kDa with KKE/D repeat) |
| 1416606_s_at | Mm.28203 | Nola2 | Hs.27222 | NOLA2 | Nucleolar protein family A, member 2 (H/ACA small nucleolar RNPs) |
| 1449140_at | Mm.276504 | Nudcd2 | Hs.140443 | NUDCD2 | NudC domain containing 2 |
| 1428277_at | Mm.387724 | Otud6b | Hs.30532 | OTUD6B | OTU domain containing 6B |
| 1435368_a_at | Mm.277779 | Parp1 | Hs.177766 | PARP1 | poly-(ADP-ribose) polymerase family, member 1 |
| 1452620_at | Mm.29856 | Pck2 | Hs.75812 | PCK2 | Phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| 1426838_at | Mm.37562 | Pold3 | Hs.82502 | POLD3 | Polymerase (DNA-directed), delta 3, accessory subunit |
| 1427094_at | Mm.9199 | Pole2 | Hs.162777 | POLE2 | Polymerase (DNA directed), epsilon 2 (p59 subunit) |
| 1449648_s_at | Mm.3458 | Rpo1–1 | Hs.584839 | POLR1C | polymerase (RNA) I polypeptide C |
| 1433552_a_at | Mm.273217 | Polr2b | Hs.602757 | POLR2B | polymerase (RNA) II (DNA directed) polypeptide B |
| 1436505_at | Mm.11815 | Ppig | Hs.470544 | PPIG | Peptidylprolyl isomerase G (cyclophilin G) |
| 1428265_at | Mm.7726 | Ppp2r1b | Hs.546276 | PPP2R1B | protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform |
| 1423775_s_at | Mm.227274 | Prc1 | Hs.567385 | PRC1 | protein regulator of cytokinesis 1 |
| 1452032_at | Mm.30039 | Prkar1a | Hs.280342 | PRKAR1A | Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue-specific extinguisher 1) |
| 1451576_at | Mm.71 | Prkdc | Hs.491682 | PRKDC | Protein kinase, DNA-activated, catalytic polypeptide |
| 1435859_x_at | Mm.2462 | Psmc2 | Hs.437366 | PSMC2 | Proteasome (prosome, macropain) 26S subunit, ATPase, 2 |
| 1426631_at | Mm.58660 | Pus7 | Hs.520619 | PUS7 | Pseudouridylate synthase 7 homolog (S. cerevisiae) |
| 1448899_s_at | Mm.204634 | Rad51ap1 | Hs.591046 | RAD51AP1 | RAD51-associated protein 1 |
| 1423700_at | Mm.12553 | Rfc3 | Hs.115474 | RFC3 | Replication factor C (activator 1) 3 |
| 1456375_x_at | Mm.314056 | Trim27 | Hs.440382 | RFP | Tripartite motif-containing 27 |
| 1439403_x_at | Mm.435574 | Rnf12 | Hs.653288 | RNF12 | Ring finger protein 12 |
| 1437309_a_at | Mm.180734 | Rpa1 | Hs.461925 | RPA1 | Replication protein A1 |
| 1453362_x_at | Mm.16775 | Rps24 | Hs.356794 | RPS24 | Ribosomal protein S24 |
| 1416276_a_at | Mm.66 | Rps4x | Hs.446628 | RPS4X | Ribosomal protein S4, X-linked |
| 1416120_at | Mm.99 | Rrm2 | Hs.226390 | RRM2 | Ribonucleotide reductase M2 polypeptide |
| 1422864_at | Mm.4081 | Runx1 | Hs.149261 | RUNX1 | Runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) |
| 1420824_at | Mm.33903 | Sema4 d | Hs.655281 | SEMA4D | Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| 1434972_x_at | Mm.391719 | Sfrs1 | Hs.68714 | SFRS1 | Splicing factor, arginine/serine-rich 1 (splicing factor 2, alternate splicing factor) |
| 1417623_at | Mm.399997 | Slc12a2 | Hs.162585 | SLC12A2 | Solute carrier family 12 (sodium/potassium/chloride transporters), member 2 |
| 1418326_at | Mm.27943 | Slc7a5 | Hs.513797 | SLC7A5 | Solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 |
| 1422771_at | Mm.325757 | Smad6 | Hs.153863 | SMAD6 | SMAD family member 6 |
| 1424206_at | Mm.246803 | Smarca5 | Hs.589489 | SMARCA5 | SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a, member 5 |
| 1452422_a_at | Mm.1323 | Snrpb2 | Hs.280378 | SNRPB2 | Small nuclear ribonucleoprotein polypeptide B |
| 1419156_at | Mm.240627 | Sox4 | Hs.643910 | SOX4 | SRY (sex determining region Y)-box 4 |
| 1433502_s_at | Mm.220843 | Tsr1 | Hs.388170 | SRR | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) |
| 1415849_s_at | Mm.378957 | Stmn1 | Hs.693592 | STMN1 | Stathmin 1/oncoprotein 18 |
| 1450743_s_at | Mm.260545 | Syncrip | Hs.571177 | SYNCRIP | Synaptotagmin binding, cytoplasmic RNA interacting protein |
| 1423601_s_at | Mm.2215 | Tcof1 | Hs.519672 | TCOF1 | Treacher Collins-Franceschetti syndrome 1 |
| 1416358_at | Mm.34564 | 0610009O03Rik | Hs.632581 | TETRAN | Tetracycline transporter-like protein (TETRAN) |
| 1434317_s_at | Mm.272025 | Tex10 | Hs.494648 | TEX10 | Testis expressed sequence 10 |
| 1426397_at | Mm.172346 | Tgfbr2 | Hs.82028 | TGFBR2 | Transforming growth factor, beta receptor II |
| 1424641_a_at | Mm.219648 | Thoc1 | Hs.654460 | THOC1 | THO complex 1 |
| 1427318_s_at | Mm.34674 | Fer1l3 | Hs.500572 | FER1L3 | Fer-1-like 3, myoferlin (C. elegans) |
| 1449041_a_at | Mm.27063 | Trip6 | Hs.534360 | TRIP6 | Thyroid hormone receptor interactor 6 |
| 1437906_x_at | Mm.19169 | Txnl1 | Hs.114412 | TXNL1 | Thioredoxin-like 1 |
| 1422842_at | Mm.3065 | Xrn2 | Hs.255932 | XRN2 | 5′-3′ exoribonuclease 2 |
| 1448363_at | Mm.221992 | Yap1 | Hs.503692 | YAP1 | Yes-associated protein 1 |
| 1427208_at | Mm.289103 | Zfp451 | Hs.485628 | ZNF451 | Zinc finger protein 451 |
| 1416757_at | Mm.335237 | Zwilch | Hs.21331 | ZWILCH | Zwilch, kinetochore associated, homolog (Drosophila) |
For simplicity, the gene description is only given for the human entry.
*
Unigene build 163;
†
Unigene build 202.