Table 2.
The Cross-Species Conserved 166-Gene Signature: Down-Regulated Genes
| Mouse
|
Human
|
||||
|---|---|---|---|---|---|
| Probe ID | Unigene* | Gene | Unigene† | Gene | Description |
| 1424600_at | Mm.213898 | Abp1 | Hs.647097 | ABP1 | Amiloride binding protein 1 [amine oxidase (copper-containing)] |
| 1427034_at | Mm.754 | Ace | Hs.298469 | ACE | Angiotensin I-converting enzyme (peptidyldipeptidase A) 1 |
| 1418553_at | Mm.170461 | Arhgef18 | Hs.465761 | ARHGEF18 | Rho/rac guanine nucleotide exchange factor (GEF) 18 |
| 1459924_at | Mm.340818 | Atp6v0a1 | Hs.463074 | ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| 1416582_a_at | Mm.4387 | Bad | Hs.370254 | BAD | BCL2-antagonist of cell death |
| 1423635_at | Mm.103205 | Bmp2 | Hs.73853 | BMP2 | Bone morphogenetic protein 2 |
| 1456616_a_at | Mm.726 | Bsg | Hs.591382 | BSG | BSG: Basigin (Ok blood group) |
| 1424226_at | Mm.218590 | 9030617O03Rik | Hs.309849 | C14orf159 | Chromosome 14 open reading frame 159 |
| 1427944_at | Mm.150568 | C1qdc1 | Hs.234355 | C1QDC1 | C1q domain containing 1 |
| 1449248_at | Mm.177761 | Clcn2 | Hs.436847 | CLCN2 | Chloride channel 2 |
| 1416565_at | Mm.400 | Cox6b1 | Hs.431668 | COX6B1 | Cytochrome c oxidase subunit Vib polypeptide 1 (ubiquitous) |
| 1420617_at | Mm.339792 | Cpeb4 | Hs.127126 | CPEB4 | Cytoplasmic polyadenylation element binding protein 4 |
| 1415677_at | Mm.21623 | Dhrs1 | Hs.348350 | DHRS1 | Dehydrogenase/reductase (SDR family) member 1 |
| 1416697_at | Mm.1151 | Dpp4 | Hs.368912 | DPP4 | Dipeptidylpeptidase 4 (CD26, adenosine deaminase complexing protein 2) |
| 1450314_at | Mm.140332 | Dqx1 | Hs.191705 | DQX1 | DEAQ box polypeptide 1 (RNA-dependent ATPase) |
| 1421136_at | Mm.9478 | Edn3 | Hs.1408 | EDN3 | Endothelin 3 |
| 1423005_a_at | Mm.264215 | Espn | Hs.147953 | ESPN | Espin |
| 1421969_a_at | Mm.256025 | Faah | Hs.528334 | FAAH | Fatty acid amide hydrolase |
| 1452117_a_at | Mm.170905 | Fyb | Hs.370503 | FYB | FYN binding protein (FYB-120/130) |
| 1436889_at | Mm.338713 | Gabra1 | Hs.175934 | GABRA1 | γ -Aminobutyric acid (GABA) A receptor, alpha 1 |
| 1423236_at | Mm.30249 | Galnt1 | Hs.514806 | GALNT1 | UDP-N-acetyl-α -d-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) |
| 1418863_at | Mm.247669 | Gata4 | Hs.243987 | GATA4 | GATA binding protein 4 |
| 1429076_a_at | Mm.283495 | Gdpd2 | Hs.438712 | GDPD2 | Glycerophosphodiester phosphodiesterase domain containing 2 |
| 1449144_at | Mm.260925 | Gna11 | Hs.654784 | GNA11 | Guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| 1419371_s_at | Mm.195451 | Gosr2 | Hs.463278 | GOSR2 | Golgi SNAP receptor complex member 2 |
| 1416416_x_at | Mm.37199 | Gstm1 | Hs.75652 | GSTM5 | Glutathione S-transferase M5 |
| 1425343_at | Mm.41506 | Hdhd3 | Hs.7739 | HDHD3 | Haloacid dehalogenase-like hydrolase domain containing 3 |
| 1422527_at | Mm.16373 | H2-DMa | Hs.351279 | HLA-DMA | HLA-DMA: Major histocompatibility complex, class II, DM alpha |
| 1419455_at | Mm.4154 | Il10rb | Hs.418291 | IL10RB | Interleukin 10 receptor, beta |
| 1418265_s_at | Mm.1149 | Irf2 | Hs.374097 | IRF2 | Interferon regulatory factor 2 |
| 1433775_at | Mm.331907 | C77080 | Hs.591502 | KIAA1522 | KIAA1522 |
| 1425547_a_at | Mm.279599 | Klc4 | Hs.408062 | KLC4 | Kinesin light chain 4 |
| 1451322_at | Mm.28108 | Cmbl | Hs.192586 | CMBL | Carboxymethylenebutenolidase homolog (Pseudomonas) |
| 1425780_a_at | Mm.241387 | Tmem167 | Hs.355606 | TMEM167 | Transmembrane protein 167 |
| 1425704_at | Mm.192213 | BC022224 | Hs.462859 | MGC4172 | Short-chain dehydrogenase/reductase |
| 1425930_a_at | Mm.628 | Mlx | Hs.383019 | MLX | MAX-like protein X |
| 1450376_at | Mm.2154 | Mxi1 | Hs.501023 | MXI1 | MAX interactor 1 |
| 1425230_at | Mm.31686 | Nags | Hs.8876 | NAGS | N-Acetylglutamate synthase |
| 1448331_at | Mm.29683 | Ndufb7 | Hs.532853 | NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7 |
| 1415821_at | Mm.15125 | Nptn | Hs.187866 | NPTN | Neuroplastin |
| 1451274_at | Mm.276348 | Ogdh | Hs.488181 | OGDH | Oxoglutarate (α- ketoglutarate) dehydrogenase (lipoamide) |
| 1417677_at | Mm.32744 | Opn3 | Hs.534399 | OPN3 | Opsin 3 |
| 1449330_at | Mm.29872 | Pdzd3 | Hs.374726 | PDZD3 | PDZ domain containing 3 |
| 1435872_at | Mm.328931 | Pim1 | Hs.81170 | PIM1 | Pim-1 oncogene |
| 1425542_a_at | Mm.240396 | Ppp2r5c | Hs.368264 | PPP2R5C | Protein phosphatase 2, regulatory subunit B′, gamma isoform |
| 1422847_a_at | Mm.2314 | Prkcd | Hs.155342 | PRKCD | Protein kinase C, delta |
| 1424456_at | Mm.4341 | Pvrl2 | Hs.655455 | PVRL2 | Poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| 1430527_a_at | Mm.261818 | Rnf167 | Hs.7158 | RNF167 | Ring finger protein 167 |
| 1448704_s_at | Mm.22362 | H47 | Hs.32148 | SELS | Selenoprotein S |
| 1448299_at | Mm.246670 | Slc1a1 | Hs.444915 | SLC1A1 | Solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| 1424441_at | Mm.330113 | Slc27a4 | Hs.656699 | SLC27A4 | Solute carrier family 27 (fatty acid transporter), member 4 |
| 1433595_at | Mm.281800 | Slc35d1 | Hs.213642 | SLC35D1 | Solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1 |
| 1421225_a_at | Mm.41044 | Slc4a4 | Hs.5462 | SLC4A4 | Solute carrier family 4, sodium bicarbonate cotransporter, member 4 |
| 1448783_at | Mm.45874 | Slc7a9 | Hs.408567 | SLC7A9 | Solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 |
| 1436797_a_at | Mm.300594 | Surf4 | Hs.512465 | SURF4 | Surfeit 4 |
| 1428095_a_at | Mm.33869 | Tmem24 | Hs.587176 | TMEM24 | Transmembrane protein 24 |
| 1417895_a_at | Mm.25295 | Tmem54 | Hs.534521 | TMEM54 | Transmembrane protein 54 |
| 1434553_at | Mm.26088 | Tmem56 | Hs.483512 | TMEM56 | Transmembrane protein 56 |
| 1420412_at | Mm.1062 | Tnfsf10 | Hs.478275 | TNFSF10 | Tumor necrosis factor (ligand) superfamily, member 10 |
| 1428327_at | Mm.305318 | Trak1 | Hs.535711 | TRAK1 | Trafficking protein, kinesin binding 1 |
| 1448737_at | Mm.18590 | Tspan7 | Hs.441664 | TSPAN7 | Tetraspanin 7 |
| 1448782_at | Mm.291015 | Txndc11 | Hs.313847 | TXNDC11 | Thioredoxin domain containing 11 |
| 1435110_at | Mm.290433 | Unc5b | Hs.585457 | UNC5B | Unc-5 homolog B |
| 1426399_at | Mm.26515 | Vwa1 | Hs.449009 | VWA1 | Von Willebrand factor A domain containing 1 |
| 1436953_at | Mm.223504 | Wipf1 | Hs.654521 | WASPIP | WAS/WASL interacting protein family, member 1 |
| 1416545_at | Mm.240076 | Zdhhc7 | Hs.592065 | ZDHHC7 | Zinc finger, DHHC-type containing 7 |
For simplicity, the gene description is only given for the human entry.
*
Unigene build 163;
†
Unigene build 202.