Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2008 May;172(5):1411–1418. doi: 10.2353/ajpath.2008.071070

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © American Society for Investigative Pathology

PMC Copyright notice

TNF inhibition reduces pericyte and endothelial cell apoptosis in type 2 diabetic retina. a: Representative image of a cleaved caspase-3-positive pericyte (upper left panel) and endothelial cell (lower left panel), phase contrast (central panel), and PAS staining (right panel). Arrow points to a cleaved caspase-3-positive microvascular cells in a diabetic specimen. b: The mean number of cleaved caspase-3-positive endothelial cells and pericytes was determined in normoglycemic rats (C), Zucker diabetic fatty rats (DM) and Zucker diabetic fatty rats treated with pegsunercept (DM + Peg). Data represent the mean ± SEM (n = 5). c: The mean number of TUNEL-positive retinal endothelial cells and pericytes was determined in normoglycemic control rats (C), ZDF diabetic rats (DM), and ZDF diabetic rats treated with pegsunercept (DM + Peg). Data represent the mean ± SEM (n = 6). *Statistically significant compared to control (P < 0.05). **Statistically significant as compared with diabetic (P < 0.05).