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. 2008 May;172(5):1411–1418. doi: 10.2353/ajpath.2008.071070

Figure 4.

Figure 4

TNF inhibition reduces pericyte ghost formation in both type 1 and type 2 diabetic animals. a: RTDs was prepared from a diabetic specimen and stained with PAS-hematoxylin. Arrow points to a pericyte ghost. The bar represents 20 μm at original magnification, ×400. b: The mean number of pericyte ghosts was determined in normoglycemic control rats (C), streptozotocin-induced diabetic rats (DM), and streptozotocin-induced diabetic rats treated with pegsunercept (DM + Peg). Data represent the mean ± SEM (n = 5). c: The mean number of pericyte ghosts was determined in normoglycemic control rats (C), ZDF diabetic rats (DM) and ZDF diabetic rats treated with pegsunercept (DM + Peg). Data represent the mean ± SEM (n = 5). *Statistically significant as compared with control (P < 0.05). **Statistically significant as compared with diabetic (P < 0.05).