Figure 1.

Analysis of DEX and LPS response in mice expressing transgenes flanked by DNA from the mouse MT locus. Adult transgenic mice were treated with DEX or LPS for 6 hr, total nucleic acid was harvested from the liver, and transgene expression was measured by solution hybridization. The values represent mean ± SEM relative to littermate controls injected with PBS; (n), number of animals per group. The flanking mouse MT locus sequences are indicated by the dashed lines; for a better depiction of these regions, see Fig. 6A.