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(a) The structure of NAT8/NAT8B cluster: NAT8/NAT8B location in chromosome 2p13.1-p12; (b) Schematic presentation of the alignment of NAT8/NAT8B and their flanking regions and the positioning of NAT8-specific PCR primers; (c) NAT8 resequencing results and SNP positions compared to dbSNP database records; (d) Missing Binding Sites for Transcription Factors (TFBS) on chromosomes carrying the minor alleles of SNPs -911, -1151 and -1153. "S" – singleton polymorphisms.
