Table 2. Univariate Analysis of MTND2*LHON4917G and other factors involved in the development of AMD in N = 280 Caucasian pairs matched on the exact Age at the Time of Examination.
Variable | Cases | Controls | p-value |
Number | N = 280 | N = 280 | |
Age at Exam, mean±sd, years | 70.0±7.6 | 70.0±7.6 | |
Race, % Caucasian | 100 | 100 | |
Gender, % Female | 62.1 | 53.2 | 0.0328 |
rs1061170, CFH, %Allele C present | 80.7 | 66.8 | 0.0002 |
rs10490924 LOC387715, %Allele T present | 63.1 | 50.0 | <0.0001 |
APOE, % ApoE2 allele | 16.4 | 16.0 | 0.0547 |
mtDNA 4917, % G allele | 15.4 | 9.0 | 0.0140 |