Table 3. TLR1 Polymorphism Frequency in Reversal Reaction.
| SNP | Allele Frequency (%) | OR (95% CI) | P1 | Genotype frequency (%) | P2 | |||
| A3 | a | AA | Aa | aa | ||||
| Trs5743563C | ||||||||
| No reaction | 1014 (77.3) | 298 (22.7) | 1.00 | 388 (59.1) | 238 (36.3) | 30 (4.6) | ||
| Reaction | 335 (73.5) | 121 (26.5) | 1.23 (0.96–1.57) | 0.10 | 120 (52.6) | 95 (41.7) | 13 (5.7) | 0.22 |
| Ars5743565G | ||||||||
| No reaction | 1013 (77.1) | 301 (22.9) | 1.00 | 388 (59.1) | 237 (36.1) | 32 (4.9) | ||
| Reaction | 335 (73.8) | 119 (26.2) | 1.20 (0.94–1.53) | 0.15 | 120 (52.9) | 95 (41.9) | 12 (5.3) | 0.26 |
| Trs5743592C | ||||||||
| No reaction | 984 (75.2) | 324 (24.8) | 1.00 | 371 (56.7) | 242 (37.0) | 41 (6.3) | ||
| Reaction | 313 (70.2) | 133 (29.8) | 1.29 (1.02–1.64) | 0.04 | 106 (47.5) | 101 (45.3) | 16 (7.2) | 0.06 |
| Trs5743595C | ||||||||
| No reaction | 1017 (77.4) | 297 (22.6) | 1.00 | 389 (59.2) | 239 (36.4) | 29 (4.4) | ||
| Reaction | 338 (74.1) | 118 (25.9) | 1.20 (0.94–1.53) | 0.16 | 122 (53.5) | 94 (41.2) | 12 (5.3) | 0.32 |
| G743A | ||||||||
| No reaction | 710 (54.7) | 588 (45.3) | 1.00 | 202 (31.1) | 306 (47.1) | 141 (21.7) | ||
| Reaction | 262 (58.5) | 186 (41.5) | 0.86 (0.69–1.07) | 0.17 | 80 (35.7) | 102 (45.5) | 42 (18.8) | 0.39 |
| T1805G | ||||||||
| No reaction | 1117 (92.6) | 89 (7.4) | 1.00 | 523 (86.7) | 71 (11.8) | 9 (1.5) | ||
| Reaction | 396 (96.1) | 16 (3.9) | 0.51 (0.29–0.87) | 0.01 | 190 (92.2) | 16 (7.8) | 0 (0.0) | 0.05 4 |
1
P value for comparison of allele frequencies by Chi-square.
2
P value for comparison of genotype frequencies calculated by Chi-square unless otherwise indicated.
3
A denotes common allele, a denotes minor allele.
4
P value calculated by Fisher's Exact test due to small cell number.