Table 4. Frequency of TLR1 haplotypes in reversal reaction.
6 SNP Haplotypes1 | Reversal Reaction | OR (95% CI) | P3 | |
No | Yes | |||
TATTAT | 441 (37.8) | 155 (38.1) | 1.00 | |
TATTGT | 356 (30.5) | 116 (28.5) | 0.93 (0.70–1.22) | 0.68 |
CGCCGT | 259 (22.2) | 105 (25.8) | 1.15 (0.86–1.54) | 0.46 |
TATTAG | 82 (7.1) | 16 (3.9) | 0.55 (0.31–0.97) | 0.05 |
TACTGT | 26 (2.2) | 15 (3.7) | 1.64 (0.85–3.17) | 0.15 |
CGCCGG | 2 (0.1) | 0 (0.0) | 0.25 (0.00–51.20) | 0.58 |
2 SNP Haplotypes 2 | ||||
TT | 808 (68.0) | 272 (66.4) | 1.00 | |
CT | 294 (24.7) | 122 (29.7) | 1.23 (0.95–1.58) | 0.18 |
TG | 83 (7.0) | 16 (3.8) | 0.56 (0.32–0.97) | 0.05 |
CG | 3 (0.3) | 0 (0.1) | 0.41 (0.02–10.61) | 0.58 |
Order for 6 SNP haplotypes, left to right: Trs5743563C, Ars5743565G, Trs5743592C, Trs5743595C, G743A, T1805G.
Order for 2 SNP haplotypes: Trs5743592C, T1805G.
P value represents comparison of a given haplotype with the reference haplotype TATTAT.