Table 1.
Patienta | Isolate | CD4 countb | Months to AIDSc | Clinical statusd | Coreceptor usee |
G | 1228 | 260 | -9 | Chronic AS | R5 |
4481 | 5 | +26 | End-stage AIDS | R5 | |
H | 624 | 290 | -27 | Chronic AS | R5 |
3899 | 6 | +6 | End-stage AIDS | R5 | |
I | 5013 | 140 | -30 | Chronic AS | R5 |
8616 | 90 | +11 | End-stage AIDS | R5 | |
J | 1372 | 220 | -11 | Chronic AS | R5 |
5714 | 20 | +20 | End-stage AIDS | R5 | |
L | 462 | 220 | -44 | Chronic AS | R5 |
3932 | 13 | +/-0 | End-stage AIDS | R5 | |
M | 668 | 750 | -54 | Chronic AS | R5 |
7363 | 20 | +20 | End-stage AIDS | R5 | |
R | 6322 | 200 | -2 | Chronic AS | R3R5 |
8004 | 9 | +16 | End-stage AIDS | R3R5 |
a) Patient code according to [7].
b) CD4+ T cells/μl at time of virus isolation.
c) Time point of virus isolation related to months before and after AIDS diagnosis.
d) Patient status at time of virus isolation. AS = asymptomatic or with mild symptoms not classified as AIDS, AIDS = acquired immunodeficiency syndrome.
e) Coreceptor use determined by infection of U87.CD4 and GHOST coreceptor indicator cell lines expressing CCR2b, CCR3, CCR5, CXCR4, CXCR6 or BOB [7].