Table 1.
Proteins identified as Frizzled1 interactors in the split-ubiquitin screen
| Prey protein definition | Accession | Prey full length | Nub-fusion point | Pathway association with |
|---|---|---|---|---|
| Beta adaptin | AAA40797 | 937 | 155 | ? |
| Calmodulin 1 | AAP36156 | 150 | 1 | Wnt/Ca2+ signaling |
| Fibronectin precursor | CAA26536 | 2328 | 1218 | Planar cell polarity + Wnt/cAMP signaling |
| Histone deacetylase 5 | AAD29047 | 1122 | 669 | Canonical pathway |
| Hypothetical protein LOC54934 | AAH13900 | 390 | 289 | ? |
| LIM domain only 4 | AAH03600 | 165 | 41 | ? |
| Nesprin-1 | AAN60442 | 8797 | 450 | ? |
| Neurochondrin-2 | BAA77831 | 712 | 546 | Wnt/Ca2+ signaling |
| Novel protein containing a tubulin-tyrosine ligase family domain | CAI22724 | 553 | 1 | ? |
| Nucleosome assembly protein | BAA08904 | 506 | 77 | ? |
| PEG3 | AAC83176 | 615 | 414 | ? |
| Rab geranylgeranyltransferase, alpha subunit | NP_004572 | 567 | 354 | ? |
| RAC/CDC42/Rho exchange factor GEFT | AAO49463 | 580 | 206 | Wnt/Rho signaling |
| Receptor-type protein tyrosine phosphatase beta, RPTP beta, PTP zeta | AAB26530 | 2307 | 1447 | Canonical pathway |
| Tubulin, beta, 2 | AAH29529 | 445 | 1 | Canonical pathway |
| Vac14 homolog | NP_060522 | 782 | 183 | ? |
? refers to poorly characterized protein. Further experiments are needed to link it to Wnt pathway.