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. 2008 Feb 5;36(6):1805–1812. doi: 10.1093/nar/gkn011

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© 2008 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — (A) The sequence and numbering of fully modified 4′-thioDNA. (B) The H6/H8-H1′ region of the NOESY spectrum of 4′-thioDNA. The H1′ (i − 1)–H6/H8(i)–H1′ (i) connectivities are traced, the intraresidue correlation peaks being labeled with the residue numbers. The H1′–H2′ (labeled in black) and H1′–H2″(labeled in green) regions (C) and the H2″–H3′ region (D) of the DQF-COSY spectrum of 4′-thioDNA.