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. 2008 Feb 11;36(6):1900–1912. doi: 10.1093/nar/gkn044

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© 2008 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — The p53 CTD inhibits the p53/p73 response. (A) H1299 cells were infected with adenoviruses expressing GFP alone or in combination with p53, p53Δ30, p73α or p73α+30. Protein levels obtained by adenoviral infection are shown in Figure 7B. Shown are the cell cycle profiles measured 24 h after infection. (B, C) Quantitative analysis of (B) apoptosis (sub-G1) and (C) S-phase 24 h after Saos-2 cells were infected and analyzed as described in (A). The observed differences are statistically significant as determined by two-sided Student's t-test.