Table 2.
Wheel running did not ameliorate the effects of the HD mutation on body and brain weight at 9 months of age. The HD transgene affected both body weight (P < 0.001) and brain weight (P < 0.001) at 9 months of age, relative to WT littermates. NE: non-enriched (standard housed); RW: running-wheel housed.
WT | HD | |||
RW | NE | RW | NE | |
Body weight (grams) | 39.70 ± 3.01 | 32.36 ± 2.57 | 22.38 ± 1.05 | 22.54 ± 0.75 |
Brain weight (grams) | 0.54 ± 0.015 | 0.53 ± 0.008 | 0.42 ± 0.011 | 0.42 ± 0.007 |