Table 5.
Subset of differentially expressed cellular genes at each time point.
| Pathway or function | Clone or oligo name | Gene symbol | Human refseq | Fold change | Microarray | |||||
| T0 | T1 | T2 | T4 | T8 | T12 | |||||
| Class I antigenic Pathway | SS00013127 | HLA-A | NM_002116 | NS | - | - | - | -4.6 | NS | Qiagen-NRSP8 |
| SS00001303 | HLA-A | NM_002116 | NS | - | - | - | -3.8 | NS | Qiagen-NRSP8 | |
| SCAN0007.O.20 | SLA Ia | NM_002116 | - | - | - | -4.9 | -4.6 | -4.5 | SLA/PRV | |
| SCAN0032.G.07 | SLA Ia | NM_002116 | - | - | - | - | -4.0 | - | SLA/PRV | |
| SCAN0010.J.21 | SLA Ia | NM_002116 | - | - | - | - | - | -5.9 | SLA/PRV | |
| SCAA0099.O.04 | SLA-7 | NM_002116 | - | - | - | -3.5 | -3.6 | - | SLA/PRV | |
| SS00000703 | PSMB8 | NM_148919 | NS | - | - | 5.5 | 7.8 | NS | Qiagen-NRSP8 | |
| SCAC0037.O.09 | TAP1 | NM_000593 | - | - | - | - | 3.9 | - | SLA/PRV | |
| SS00010012 | TAP1 | NM_000593 | - | - | - | -7.8 | NS | Qiagen-NRSP8 | ||
| SS00002173 | TAP2 | NM_000544 | NS | - | - | -6.9 | - | NS | Qiagen-NRSP8 | |
| SS00010176 | MICB | NM_005931 | NS | - | - | 11.1 | 11.3 | NS | Qiagen-NRSP8 | |
| Class II antigenic pathway | SS00000697 | HLA-DMB | NM_002118 | NS | - | - | - | -7.7 | NS | Qiagen-NRSP8 |
| SS00000661 | HLA-DOA | NM_002119 | NS | - | - | - | 5.2 | NS | Qiagen-NRSP8 | |
| SS00000973 | HLA-DQA1 | NM_002122 | NS | - | - | - | 5.2 | NS | Qiagen-NRSP8 | |
| SCAB0137.B.15 | HLA-DOB | NM_002120 | - | - | - | -4.0 | - | - | SLA/PRV | |
| SCAC0044.H.08 | HLA-DMB | NM_002118 | - | - | - | -4.6 | - | - | SLA/PRV | |
| SS00000824 | CIITA | NM_000246 | NS | - | - | - | 3.3 | NS | Qiagen-NRSP8 | |
| Immunity (other genes) | SS00010182 | CD4 | NM_000616 | NS | - | 5.1 | 14.6 | 14.1 | NS | Qiagen-NRSP8 |
| SS00009986 | CD69 | NM_001781 | NS | - | - | -3.1 | -5.9 | NS | Qiagen-NRSP8 | |
| SS00006217 | CLEC2L | XM_498242 | NS | - | 3.2 | 11.8 | 16.1 | NS | Qiagen-NRSP8 | |
| SS00009653 | CLEC5A | NM_013252 | NS | - | - | -4.0 | -6.9 | NS | Qiagen-NRSP8 | |
| SS00002913 | IK | NM_006083 | NS | - | - | - | 5.0 | NS | Qiagen-NRSP8 | |
| SS00010183 | ICAM1 | NM_000201 | NS | - | - | -4.2 | -9.2 | NS | Qiagen-NRSP8 | |
| SS00003797 | IFNAR2 | NM_207585 | NS | - | - | 3.5 | 7.9 | NS | Qiagen-NRSP8 | |
| SS00010797 | IFNGR2 | NM_005534 | NS | - | - | - | -6.1 | NS | Qiagen-NRSP8 | |
| SS00002396 | IRF1 | NM_002198 | NS | - | - | -5.0 | -9.3 | NS | Qiagen-NRSP8 | |
| SS00009562 | IRF2 | NM_002199 | NS | - | - | -4.4 | -10.8 | NS | Qiagen-NRSP8 | |
| SS00000183 | IRF3 | NM_001571 | NS | - | - | - | -3.9 | NS | Qiagen-NRSP8 | |
| SS00003318 | IRF5 | NM_032643 | NS | - | - | -3.5 | -7.9 | NS | Qiagen-NRSP8 | |
| SS00000904 | IFNA6 | NM_021002 | NS | - | - | - | -7.2 | NS | Qiagen-NRSP8 | |
| SS00010817 | IFI6 | NM_002038 | NS | - | - | 6.5 | 12.5 | NS | Qiagen-NRSP8 | |
| SS00010811 | IFI30 | NM_006332 | NS | - | - | - | -6.1 | NS | Qiagen-NRSP8 | |
| SS00001608 | ISGF3G | NM_006084 | NS | - | - | - | 3.9 | NS | Qiagen-NRSP8 | |
| SS00009843 | IL12A | NM_000882 | NS | - | - | -3.3 | -17.1 | NS | Qiagen-NRSP8 | |
| SS00009841 | IL12B | NM_002187 | NS | - | - | -7.9 | -17.1 | NS | Qiagen-NRSP8 | |
| SS00008021 | TLR8 | NM_016610 | NS | - | - | -4.6 | -5.9 | NS | Qiagen-NRSP8 | |
| SCAA0015.B.22 | PPIA | NM_021130.3 | - | - | - | -3.9 | -4.8 | -4.8 | SLA/PRV | |
| SCAU0001.B.05 | PPIA | NM_021130.3 | - | - | - | -3.6 | -4.3 | -4.7 | SLA/PRV | |
| SS00003892 | PPIL1 | NM_016059 | NS | - | - | - | 3.2 | NS | Qiagen-NRSP8 | |
| SS00001759 | PPIL2 | NM_148176 | NS | - | - | - | 4.1 | NS | Qiagen-NRSP8 | |
| SS00001178 | PPIF | NM_005729 | NS | - | - | - | -3.8 | NS | Qiagen-NRSP8 | |
| SS00001241 | PPIG | NM_004792 | NS | - | - | - | -4.3 | NS | Qiagen-NRSP8 | |
| SS00005782 | PPIH | NM_006347 | NS | - | - | - | 5.1 | NS | Qiagen-NRSP8 | |
| SS00006083 | FKBP3 | NM_002013 | NS | - | - | - | -8.3 | NS | Qiagen-NRSP8 | |
| SS00002702 | FKBP4 | NM_002014 | NS | - | 3.6 | 13.0 | 14.3 | NS | Qiagen-NRSP8 | |
| Apoptosis | SS00003686 | BNIP1 | NM_001205 | NS | - | - | - | -6.1 | NS | Qiagen-NRSP8 |
| SS00000546 | BAK1 | NM_001188 | NS | - | - | - | -4.3 | NS | Qiagen-NRSP8 | |
| SS00010935 | BCLAF1 | NM_014739 | NS | - | -4.0 | -4.6 | -6.6 | NS | Qiagen-NRSP8 | |
| SS00001150 | BCL2L1 | NM_138578 | NS | - | - | -3.4 | -6.5 | NS | Qiagen-NRSP8 | |
| SS00005026 | BCL2L14 | NM_138723 | NS | - | - | - | -5.8 | NS | Qiagen-NRSP8 | |
| SS00000872 | CASP1 | NM_033293 | NS | - | - | 3.6 | 5.0 | NS | Qiagen-NRSP8 | |
| SS00000520 | CASP3 | NM_032991 | NS | - | - | - | -0.7 | NS | Qiagen-NRSP8 | |
| SS00004783 | CASP7 | NM_001227 | NS | - | - | - | 6.7 | NS | Qiagen-NRSP8 | |
| SS00003624 | CARD6 | NM_032587 | NS | - | - | 3.5 | 6.6 | NS | Qiagen-NRSP8 | |
| SS00000561 | DDX58 | NM_014314 | NS | - | -3.1 | -4.3 | -8.3 | NS | Qiagen-NRSP8 | |
| SS00000329 | FAF1 | NM_007051 | NS | - | - | - | 5.8 | NS | Qiagen-NRSP8 | |
| SS00012494 | FAIM2 | NM_012306 | NS | - | - | -4.6 | -10.7 | NS | Qiagen-NRSP8 | |
| ER* stress | SS00000384 | EIF2A | NM_032025 | NS | - | - | 3.7 | 7.1 | NS | Qiagen-NRSP8 |
| Pathway | SS00008645 | XBP1 | NM_005080 | NS | - | - | - | -6.4 | NS | Qiagen-NRSP8 |
| SS00004223 | ATF4 | NM_182810 | NS | - | - | - | -4.1 | NS | Qiagen-NRSP8 | |
| SS00001308 | HSPA8 | NM_006597 | NS | - | - | - | 3.6 | NS | Qiagen-NRSP8 | |
| Nucleic acid | SCAB0073.K.18 | HIST1H2BK | NM_080593 | - | - | - | -3.9 | -6.8 | -4.4 | SLA/PRV |
| Binding | SCAA0122.E.09 | HIST1H2AL | NM_003511 | - | - | - | -3.9 | -6.0 | -3.7 | SLA/PRV |
| SCAB0057.M.21 | HIST1H4J | NM_021968 | - | - | - | -5.1 | -4.4 | -4.0 | SLA/PRV | |
| SCAB0015.G.08 | HIST3H2BB | NM_021968 | - | - | - | - | -4.2 | -5.4 | SLA/PRV | |
| SS00005067 | HDAC2 | NM_001527 | NS | - | 4.6 | 8.3 | 9.1 | NS | Qiagen-NRSP8 | |
| SS00004784 | HDAC3 | NM_003883 | NS | - | - | -5.5 | -10.9 | NS | Qiagen-NRSP8 | |
| SS00007434 | HDAC6 | NM_006044 | NS | - | - | -3.7 | -8.4 | NS | Qiagen-NRSP8 | |
| SS00003586 | HDAC9 | NM_014707 | NS | - | -3.5 | -4.8 | -10.6 | NS | Qiagen-NRSP8 | |
| SS00004682 | HDAC10 | NM_032019 | NS | - | - | - | 3.9 | NS | Qiagen-NRSP8 | |
| SS00007084 | STAT1 | NM_007315 | NS | - | - | - | 7.6 | NS | Qiagen-NRSP8 | |
| SS00008286 | STAT3 | NM_139276 | NS | - | - | - | -4.4 | NS | Qiagen-NRSP8 | |
| SS00008435 | STAT5B | NM_012448 | NS | - | - | -5.3 | -9.9 | NS | Qiagen-NRSP8 | |
| SS00004427 | STAT6 | NM_003153 | NS | - | - | - | -4.6 | NS | Qiagen-NRSP8 | |
| Cytoskeleton | SS00003440 | ACTC1 | NM_005159 | NS | - | - | - | -8.9 | NS | Qiagen-NRSP8 |
| SS00013114 | ACTG1 | NM_001614 | NS | 3.3 | 6.9 | 19.4 | 18.2 | NS | Qiagen-NRSP8 | |
| SS00002774 | ACTL6A | NM_004301 | NS | - | - | - | 3.6 | NS | Qiagen-NRSP8 | |
| SS00005476 | ACTRT2 | NM_080431 | NS | - | - | - | -7.2 | NS | Qiagen-NRSP8 | |
| SS00007431 | ACTA4 | NM_00492 | NS | - | - | -3.7 | -3.9 | NS | Qiagen-NRSP8 | |
| SS00011046 | MYO1D | NM_015194 | NS | - | - | -4.7 | -10.2 | NS | Qiagen-NRSP8 | |
| SS00007818 | MYO5A | NM_000259 | NS | - | - | -3.7 | -9.8 | NS | Qiagen-NRSP8 | |
* ER: Endoplasmic Reticulum
NS: Not Studied
-: not differentially express