Table 4.
Differentially expressed genes between breeds at FDR < 0.05
| Gene | Symbol | Probe | z-score | Function, GO-process |
| Prostaglandin E synthase 2 | PTGS2 | Ssc.25850.1.A1_at | 10.20 | Regulation of inflammatory response/prostaglandin-endoperoxide synthase activity |
| Hypothetical protein DKFZp313A2432 | Q8NHG7 | Ssc.29609.2.A1_at | - 9.11 | Unknown |
| ATPase, H+ transporting, lysosomal 31 kDa, V1 subunit E1 | ATP6V1G2 | Ssc.12005.1.A1_at | 8.97 | Purine ribonucleotide metabolism/ion transporter activity |
| Synovial sarcoma, X breakpoint 2 interacting protein | SSX2IP | Ssc.28283.1.A1_at | 8.89 | Cell adhesion |
| Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | SEMA3A | Ssc.29388.1.A1_at | 7.74 | Cell differentiation (nervous system development) |
| DIDO1 death inducer-obliterator 1 | DATF1 | Ssc.14412.1.A1_at | 7.46 | Apoptosis (M. musculus)/regulation of transcription, DNA-dependent |
| Hypothetical protein DKFZp313A2432 | Q8NHG7 | Ssc.29609.1.S1_at | - 7.18 | Unknown |
| Immunoglobulin heavy constant mu | IGHM | Ssc.7706.1.A1_at | 7.09 | Response to biotic stimulus/signal transducer activity |
| Major histocompatibility complex, class I, B | HLA-B | Ssc.18554.1.S1_x_at | - 6.61 | Antigen processing, endogenous antigen via MHC class I/MHC class I receptor activity |
| Armadillo repeat containing, X-linked 1 | ARMCX1 | Ssc.5616.1.S1_at | - 6.42 | Cellular component |
| Tousled-like kinase 2 | TLK2 | Ssc.30422.1.A1_at | 6.36 | Establishment and/or maintenance of chromatin architecture/transferase activity, transferring phosphorus-containing groups |
| Follistatin-like 4 | FSTL4 | Ssc.11743.1.S1_at | - 6.15 | Calcium ion binding |
| Hypothetical protein | Q8N5E3 | Ssc.1256.1.A1_at | - 6.03 | Unknwon |
| Transcription factor CP2 | TFCP2 | Ssc.7954.1.A1_at | - 5.83 | Regulation of nucleic acid metabolism/transcription regulator activity |
| Major histocompatibility complex, class I, A | HLA-A | Ssc.13780.11.S1_x_at | - 5.60 | Antigen processing, endogenous antigen via MHC class I/MHC class I receptor activity |
| Golgi phosphoprotein 4 | GOLPH4 | Ssc.25176.1.A1_at | - 5.12 | Cellular component |
| Enoyl Coenzyme A hydratase domain containing 1 | ECHDC1 | Ssc.1146.1.S1_at | 4.86 | Metabolism/catalytic activity |
| Glycoprotein M6B | GPM6B | Ssc.8133.1.A1_at | 4.85 | Cell differentiation (nervous system development)/molecular function unknown |
| Hypothetical protein | C21orf88 | Ssc.22421.1.A1_at | - 4.68 | Unknwon |
| Polo-like kinase 2 | PLK2 | Ssc.29934.1.A1_at | - 4.67 | Positive regulation of signal transduction/transferase activity, transferring phosphorus-containing groups |
| Hypothetical protein | Q9NV98 | Ssc.5839.2.A1_at | - 4.67 | Unknwon |
| Lysozyme | LYZ | Ssc.670.1.S1_at | - 4.58 | Cellular catabolism (cell death)/hydrolase activity, acting on glycosyl bonds |
| RAB18, member RAS oncogene family | RAB18 | Ssc.30567.1.A1_at | - 4.56 | Endocytosis/pyrophosphatase activity |
| Zinc finger protein 12 | ZNF12 | Ssc.10665.1.A1_at | - 4.56 | Regulation of cellular process/zinc ion binding |
| Splicing factor, arginine/serine-rich 2, interacting protein | SFRS2IP | Ssc.12708.1.A1_at | - 4.50 | mRNA processing |
| Immunoglobulin heavy constant mu | IGHM | Ssc.11070.1.S1_at | - 4.46 | Response to biotic stimulus/signal transducer activity |
| Synapsin III | SYN3 | Ssc.3880.1.S1_at | -4.43 | Regulation of neurotransmitter levels (transmission of nerve impulse)/purine nucleotide binding |
| Deleted in liver cancer 1 | DLC1 | Ssc.18150.1.A1_at | - 4.40 | Negative regulation of growth/enzyme regulator activity |
| DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | DDX17 | Ssc.8674.1.A1_at | 4.24 | Nucleobase, nucleoside, nucleotide and nucleic acid metabolism/nucleoside-triphosphatase activity |
| Potassium channel modulatory factor 1 | KCMF1 | Ssc.25963.1.A1_at | 4.16 | Channel or pore class transporter activity |
| Mitochondrial carrier homolog 2 | MTCH2 | Ssc.6054.2.S1_at | - 4.12 | Transport |
| Cytoskeleton-associated protein 4 | CKAP4 | Ssc.2147.2.A1_at | 4.09 | Cellular component |
| Blood vessel epicardial substance | BVES | Ssc.15540.1.A1_at | - 3.82 | Muscle development |
z – scores correspond to Large White minus Iberian contrasts.