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Molecules under investigation for disc therapy
| Category | Molecule |
|---|---|
| Anti-catabolic | TIMP-1,-2,-3 |
| Anti-TNF-alpha | |
| Anti-MMPs (CPA-926) | |
| Mitogens | IGF-1 |
| PDGF | |
| EGF | |
| FGF | |
| Morphogen | TGF-beta |
| BMP-2 | |
| BMP-7 (OP-1) | |
| BMP-13 (GDF-6 aka CDMP-2) | |
| GDF-5 (CDMP-1) | |
| Intracellular regulators | Link N |
| SMADs | |
| Sox9 | |
| LMP-1 |
