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Impaired HSV-specific pCTL and pProlif responses in HIV+ individuals. The HSV-specific pCTL frequency per million CD8s from PBMC (A) and the HSV-specific pProlif frequency per million PBMC (B) were measured in individuals who were HSV-seronegative and HIV− (HSV-HIV−), HSV-seropositive and HIV− (HSV+HIV−), or HSV-seropositive and HIV-positive (HSV+HIV+). The median precursor frequency in each group of individuals is displayed. pCTL data for HSV-HIV− and HSV+HIV− are from ref. 16.
