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. 1997 Sep 16;94(19):10385–10390. doi: 10.1073/pnas.94.19.10385

Figure 1.

Figure 1

Transmission electron micrographs of apoptotic RAW264.7 macrophages infected with Y. pseudotuberculosis. Macrophages were infected with YPIIIpIB1 wild-type Y. pseudotuberculosis, YPIIIp506 (ypkAyopJ mutant), YPIIIp503 (yopEyopH mutant), or YPIIIpIB71 Yop mutant for 6 h. Note the chromatin condensation, cytoplasmic vacuolization, and swollen endoplasmic reticulum in macrophages infected with YPIIIpIB1 and YPIIIp503. In contrast, the macrophages infected with YPIIIp506 or YPIIIpIB71 appear normal despite the presence of bacteria.