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. 1997 Sep 16;94(19):10455–10460. doi: 10.1073/pnas.94.19.10455

Figure 3.

Figure 3

Blockade of leptin–CCK interaction by the CCK-A receptor antagonist devazepide or by systemic capsaicin in lean mice (+/+). After 10-min pretreatment with L-365,260 (1 mg/kg, i.p.), 10-min pretreatment with devazepide (1 mg/kg, i.p.), 7-day pretreatment with capsaicin (50 mg/kg, s.c.), or pooled vehicles, 24-hr fasted mice received a single i.p. injection of either vehicle plus vehicle or leptin (120 μg/kg) plus CCK (3.5 μg/kg) and were exposed to food for 2 hr. Data are mean ± SEM of 6–11 mice per group. ∗, P < 0.05 vs. all other groups [ANOVA, F(7,65) = 24.694].