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Dietary restriction in adult Drosophila when dFOXO is over-expressed in fat body by induction with RU486 relative to the same genotype without RU486 (vehicle only control). Mean lifespan with standard error. Asterisks indicate yeast concentrations where survival differed significantly by log-rank test (*P < 0.05; **P < 0.01; ***P < 0.0001). (A) Over-expression in the head fat body via P{Switch}S132. (B) Over-expression in visceral fat body via P{Switch}S1106.
