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. 2002 Nov 22;546(Pt 1):165–173. doi: 10.1113/jphysiol.2002.030841

Figure 3. TG synapses demonstrate pronounced neurotransmission depression in cut muscle preparations.

Figure 3

A, examples of trains of PSPs evoked in cut muscle preparations. Trains consisted of 15 stimuli at 50 Hz with 10 s intertrain intervals. For clarity, stimulation artifacts were omitted. B, average amplitude (± s.e.m.) of the first PSP in the train. In order to reduce PSP variability resulting from differences in membrane potentials, amplitudes were scaled to a driving force at a membrane potential of - 50 mV, assuming zero as the synaptic reversal potential (Linder & Quastel, 1978). n = 44 and 45 cells from 9 WT and 9 TG muscles. C, time course of PSP decay during the train. PSPs are normalized to the first PSP in the train. *P < 0.05, compared with WT group, two-tailed t test. D, semi-logarithmic plot of PSP values (extrapolated steady state levels were subtracted). Time constants derived from the slope of the regression. P < 0.05 (F test).