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. 2003 Jan 17;547(Pt 2):649–663. doi: 10.1113/jphysiol.2002.024760

Figure 9. Biochemical determination of muscle oxidative capacity.

Figure 9

Whole muscle succinate dehydrogenase (SDH) activity was measured in SOL muscle from transgenic (TG) mice from the 6412 and 6418 lines and the 6412 × 6418 cross compared to wild-type (WT) mice to determine whether there was a dose-response relationship with PV expression. A, average data for SDH activity for each TG line. B, representative Western blot of SOL muscle from the 6412 and 6412 × 6418 TG lines shows the level of PV expression (endogenous PV (PVend) and PV transgene (PV-HA)) relative to actin expression. C, there was a strong negative correlation (r=−0.975) between total PV (endogenous +PV-HA) and whole muscle SDH activity. Values shown in bar graphs are means ±s.e.m.*P < 0.05vs. WT.