Table 1.

The midpoint of steady-state of fast inactivation (Inactivation V_0.5(mV))and steady-state activation curves (Activation V_0.5(mV)), time course of fast inactivation (τ_h1(ms)) and recovery from inactivation (τ_rec (ms))

	35°C	25°C	15°C
Inactivation V0.5 (mV)
WT	−51.4 ± 0.6	−51.5 ± 0.4	−50.7 ± 1.5
MV	−61.8 ± 3.0	−63.6 ± 3.4	−61.8 ± 1.3
RH	−64.5 ± 2.9	−62.3 ± 5.9	−62.4 ± 1.2
Activation V0.5 (mV)
WT	−15.0 ± 1.8	−13.9 ± 0.6	−15.1 ± 2.8
MV	−14.8 ± 1.9	−13.8 ± 0.5	−15.0 ± 3.4
RH	−18.2 ± 1.5	−21.7 ± 0.9	−36.3 ± 0.7
τh1 (ms)
WT	0.17 ± 0.01	0.22 ± 0.01	0.66 ± 0.03
MV	0.25 ± 0.03	0.55 ± 0.01	0.87 ± 0.05
RH	0.8 ± 0.2	1.32 ± 0.11	3.44 ± 1.15
τrec (ms)
WT	1.06 ± 0.53	1.6 ± 0.59	6.45 ± 0.53
MV	0.72 ± 0.26	1.50 ± 0.33	3.45 ± 0.46
RH	0.57 ± 0.3	1.19 ± 0.2	2.91 ± 0.3

The data are means ±s.e.m. for all three channel types and at three temperatures (15,25 and 35 °C).