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. 2003 Mar 14;548(Pt 2):361–371. doi: 10.1113/jphysiol.2003.038844

Figure 6. Effects of internal spermine on outward currents through WT-(D172N)2-WT channels.

Figure 6

A, outward currents at +42 mV in the presence of spermine. The open time decreased with increasing spermine concentration. B, the averaged (n = 3–5) steady-state open probability was plotted against the membrane potential. The voltages of half-activation and slope factors were +55.0 mV and 9.9 mV in the control (▪), +46.5 mV and 8.9 mV with 1 nm spermine (•), +36.6 mV and 9.7 mV with 10 nm spermine (▴) and +20.9 mV and 9.7 mV with 100 nm spermine (▾).