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. 2003 Mar 14;548(Pt 2):361–371. doi: 10.1113/jphysiol.2003.038844

Figure 9. Effects of internal spermine on outward currents through D172N channels.

Figure 9

A, outward currents at +42 mV in the presence of spermine. Spermine decreased the open time in a concentration-dependent manner and induced a short-lived blocked state. B, the averaged (n = 3–10) steady-state open probability was plotted against membrane potential. The voltages of half-activation and slope factors were +76.7 mV and 14.5 mV in the control (▪), +55.6 mV and 10.0 mV with 10 nm spermine (•) and +40.4 mV and 6.6 mV with 100 nm spermine (▴).