Table 1.
Gastrocnemius | ||||||
---|---|---|---|---|---|---|
Red (IIa) | White (IIb) | Soleus (I) | ||||
Rested | Contracted | Rested | Contracted | Rested | Contracted | |
Non-steady-state analysis (90 min) | ||||||
FC2 | 0.502 ± 0.067b | 0.483 ± 0.050b | 0.296 ± 0.018ac | 0.278 ± 0.065ac | 0.516 ± 0.15b | 0.550 ± 0.072b |
FCO | 0.498 ± 0.067b | 0.517 ± 0.050b | 0.704 ± 0.018ac | 0.722 ± 0.065ac | 0.484 ± 0.15b | 0.450 ± 0.072b |
Steady-state analysis (90 min) | ||||||
FC2 | 0.442 ± 0.063b | 0.432 ± 0.043b | 0.274 ± 0.044ac | 0.265 ± 0.046ac | 0.482 ± 0.11b | 0.477 ± 0.089b |
FCO | 0.558 ± 0.063b | 0.568 ± 0.043b | 0.726 ± 0.044ac | 0.735 ± 0.046ac | 0.518 ± 0.11b | 0.523 ± 0.089b |
Non-steady-state analysis (105 min) | ||||||
FC2 | 0.592 ± 0.12b | 0.526 ± 0.071b | 0.250 ± 0.035ac | 0.258 ± 0.10ac | 0.594 ± 0.099b | 0.588 ± 0.11b |
FCO | 0.408 ± 0.12b | 0.474 ± 0.071b | 0.750 ± 0.035ac | 0.742 ± 0.10ac | 0.406 ± 0.099b | 0.412 ± 0.11b |
Steady-state analysis (105 min) | ||||||
FC2 | 0.489 ± 0.070b | 0.469 ± 0.051b | 0.252 ± 0.030ac | 0.285 ± 0.072ac | 0.555 ± 0.089b | 0.550 ± 0.072b |
FCO | 0.511 ± 0.070b | 0.531 ± 0.051b | 0.748 ± 0.030ac | 0.715 ± 0.072ac | 0.445 ± 0.089b | 0.450 ± 0.072b |
Results are listed as means ±s.d. (n = 5). FC2 represents the fractional enrichment of the acetyl-CoA pool from metabolism of [2,4,6,8-13C4]octanoate and FCO corresponds to the contribution from unlabelled endogenous substrates to the acetyl-CoA pool. No differences were found between non-steady-state and steady-state analyses in either 90 or 105 min infusions, nor were any differences found in 90 versus 105 min non-steady-state or steady-state values.
Different from predominantly red gastrocnemius muscle type Ha (Ha) same condition (rested or contracted)
different from white gastrocnemius muscle type IIb (IIb) same condition
different from soleus muscle same condition.