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. 2003 Feb 28;548(Pt 2):541–548. doi: 10.1113/jphysiol.2002.033761

Table 1.

Non-steady-state and steady-state analyses after infusion of [2,4,6,8-13C4]octanoate for 90 or 105 min

Gastrocnemius

Red (IIa) White (IIb) Soleus (I)



Rested Contracted Rested Contracted Rested Contracted
Non-steady-state analysis (90 min)
 FC2 0.502 ± 0.067b 0.483 ± 0.050b 0.296 ± 0.018ac 0.278 ± 0.065ac 0.516 ± 0.15b 0.550 ± 0.072b
 FCO 0.498 ± 0.067b 0.517 ± 0.050b 0.704 ± 0.018ac 0.722 ± 0.065ac 0.484 ± 0.15b 0.450 ± 0.072b
Steady-state analysis (90 min)
 FC2 0.442 ± 0.063b 0.432 ± 0.043b 0.274 ± 0.044ac 0.265 ± 0.046ac 0.482 ± 0.11b 0.477 ± 0.089b
 FCO 0.558 ± 0.063b 0.568 ± 0.043b 0.726 ± 0.044ac 0.735 ± 0.046ac 0.518 ± 0.11b 0.523 ± 0.089b
Non-steady-state analysis (105 min)
 FC2 0.592 ± 0.12b 0.526 ± 0.071b 0.250 ± 0.035ac 0.258 ± 0.10ac 0.594 ± 0.099b 0.588 ± 0.11b
 FCO 0.408 ± 0.12b 0.474 ± 0.071b 0.750 ± 0.035ac 0.742 ± 0.10ac 0.406 ± 0.099b 0.412 ± 0.11b
Steady-state analysis (105 min)
 FC2 0.489 ± 0.070b 0.469 ± 0.051b 0.252 ± 0.030ac 0.285 ± 0.072ac 0.555 ± 0.089b 0.550 ± 0.072b
 FCO 0.511 ± 0.070b 0.531 ± 0.051b 0.748 ± 0.030ac 0.715 ± 0.072ac 0.445 ± 0.089b 0.450 ± 0.072b

Results are listed as means ±s.d. (n = 5). FC2 represents the fractional enrichment of the acetyl-CoA pool from metabolism of [2,4,6,8-13C4]octanoate and FCO corresponds to the contribution from unlabelled endogenous substrates to the acetyl-CoA pool. No differences were found between non-steady-state and steady-state analyses in either 90 or 105 min infusions, nor were any differences found in 90 versus 105 min non-steady-state or steady-state values.

a

Different from predominantly red gastrocnemius muscle type Ha (Ha) same condition (rested or contracted)

b

different from white gastrocnemius muscle type IIb (IIb) same condition

c

different from soleus muscle same condition.