Table 1.
Properties of IPSCs in the absence and presence of 20 ng ml−1 BDNF
| Mean | sIPSC | sIPSC + BDNF | mlPSC | mlPSC + BDNF |
|---|---|---|---|---|
| Amplitude (pA) | 36.5 ± 3.7 | 27.3 ± 2.3* | 25.8 ± 2.1 | 20.4 ± 1.8* |
| Frequency (Hz) | 0.94 ± 0.2 | 0.34 ± 0.1* | 1.1 ± 0.3 | 0.41 ± 0.3* |
| trise (ms) | 3.2 ± 0.4 | 3.3 ± 0.4 | 3.1 ± 0.2 | 2.9 ± 0.3 |
| Tdec1, (ms) | 3.7 ± 0.6 | 3.3 ± 0.7 | 2.9 ± 0.5 | 2.7 ± 0.4 |
| Tdec2(ms) | 18.2 ± 2.8 | 16.9 ± 3.1 | 14.7 ± 2.3 | 12.9 ± 1.8 |
| No. of cells | 9 | 9 | 8 | 8 |
BDNF, brain-derived neurotrophic factor; sIPSC, spontanteous IPSC; mlPSC miniature IPSC; trise, the 10–90% rise time; Tdecl and Tdec2 are time constants of the fast and slow phases of the biexponential decay, respectively. Data are presented as means ±s.e.m.
*
Significant difference between the absence and presence of BDNF (20 ng ml−1) by paired Student's t test at P < 0.05.