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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Dev Biol. 2008 Jan 26;316(1):135–148. doi: 10.1016/j.ydbio.2008.01.017

Figure 4.

Figure 4

A tyrosine phosphatase regulates constitutive endocytosis. Panel A: Sea urchin embryos (Strongylocentrotus purpuratus) were placed in seawater containing the fluid phase marker tetramethylrhodamine dextran (3,000 mol.wt.) from 0–15 minutes post fertilization to monitor the compensatory endocytosis of cortical vesicle membranes (dark gray bars), or from 30–90 minutes post fertilization to monitor constitutive endocytosis (light gray bars). Endocytotic inhibitors were added prior to fertilization at the indicated concentrations. All points are mean ± SEM, n=5. Panel B: Extracellular tetramethylrhodamine dextran uptake by constitutive endocytosis between 30–90 minutes post fertilization was monitored as a function of phosphatase inhibitor concentration. Points are mean ± SEM, n=6.