Figure 6. Effect of local inhibition on bursting cells.

A, bursting cells (see responses to depolarizing current pulses at the bottom) were prevented from firing in the cell-attached configuration (ca) by large inhibitory components (wc traces). B, bursts of firing could be interrupted by evoked IPSPs (arrows). C, in some cells, multiple IPSPs and IPSCs were detected. D, blockage of GABA_A transmission by 100 μm picrotoxin (PTX) released population epileptiform activity (see arrows in the fp trace).