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A and C, examples of single-channel openings in the continued presence of agonist, recorded from outside-out patches of P3 Purkinje cells. Vh, −100 mV. External Ca2+, 5 mm. Baseline (closed) level is indicated as C. B and D, all-point amplitude histograms of single AMPA channel currents. The baseline noise has been subtracted from histograms after fitting Gaussian distributions to the noise components.
