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Effect of i.c.v. injection of NPY antiserum on the action of ghrelin injected i.c.v. (A) or i.v. (B) in fed animals. NPY antiserum completely blocked the effects of ghrelin injected i.c.v. and i.v.C, comparison of %MI in the antrum induced by anti-NPY antiserum (i.c.v.) + ghrelin (i.c.v.) and anti-NPY antiserum (i.c.v.) + ghrelin (i.v.). Data are compared to normal serum-injected controls. *P < 0.05; ** P < 0.01.
