Table 1.

Na_v 1.8-LI relative intensity and action potential duration

Intensity vs. AP	All			All C positive			All A positive			All A			A LTM			A Nociceptive
	P	r2	n	P	r2	n	P	r2	n	P	r2	n	P	r2	n	P	r2	n
Duration at base	****	0.4	41	ns	—	8	*	0.49	12	****	0.61	32	ns	—	21	**	0.58	11
	Slope+7.3 ± 1.4				—		Slope+23 ± 7.4			Slope+26.6 ± 3.8				—		Slope+35.6 ± 10.1
Rise time	****	0.51	41	**	0.85	8	*	0.42	12	***	0.64	32	**	0.37	21	*	0.42	11
	Slope+24.5 ± 3.8			Slope+16.3 ± 2.8			Slope+44.8 ± 16.5			Slope+60.8 ± 8.4			Slope+44.7 ± 13.3			Slope+59.4 ± 23
Fall time	***	0.31	41	ns	—	8	*	0.44	12	****	0.51	32	ns	—	21	**	0.59	11
	Slope+8.9 ± 3.1				—		Slope+40 ± 13			Slope+40.6 ± 7.2				—		Slope+65.3 ± 18

Linear regression analysis was carried out on the groups indicated to examine the correlation of Na_v 1.8-like immunoreactivity (Na_v 1.8-LI) relative intensity with AP duration at base, AP rise time and AP fall time. A-fibre unresponsive units were excluded. All neurons had membrane potentials (E_m) equal to or more negative than −50mV, except for the only C LTM (−48mV). All correlations were positive. In each case where P < 0.05, on the first line the P, r² and n values are given, and on the second line the slope is shown, ns, Not significant.

^*P < 0.05

^**P < 0.01

^***P < 0.001

^****P < 0.0001. Plots of these correlations are shown in Fig. 6.