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. 2003 Jun 18;551(Pt 1):79–92. doi: 10.1113/jphysiol.2003.046482

Figure 10. Diagram of a Calu-3 human epithelial transporting cell.

Figure 10

Evidence for all the transporting components shown, except two, is available and cited in the text. The exceptions are transmembrane carbonic anhydrase (CAIV) and cytosolic adenylyl cyclase (AC). Abbreviations are: sodium-proton exchanger, NHE1; Cl−-HCO3− exchanger, AE2; electrogenic sodium-bicarbonate transporter, NBC1; Na+-K+-2Cl− cotransporter, NKCC1; cytosolic carbonic anhydrase, CAII; transmembrane carbonic anhydrase, CAIV; cytosolic adenylyl cyclase, AC; intermediate conductance calcium-sensitive potassium channel, KCNN4; cAMP-sensitive potassium channel, KCNQ1/KCNE3; and cystic fibrosis transmembrane conductance regulator, CFTR. Sodium-potassium-ATPase is indicated by the alternating sign.