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. 2003 Jul 4;551(Pt 1):67–78. doi: 10.1113/jphysiol.2003.042598

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A, two-photon image of an FS cell filled with 200 μM calcium green. Inset shows position of stimulating electrode, S, and position of line scan through two dendrites of interest. B, calcium responses from dendrite 2 (top) and dendrite 1 (bottom) during control stimulation (black) and after addition of 50 μM CPA (grey). Note that the calcium signal was localized to dendrite 1. Decays of calcium transients were fitted to single exponentials as indicated (τ_control = 0.98 s and τ_CPA = 1.48 s). C, calcium transient from B viewed at an expanded time scale, and EPSP (bottom) at same time scale. Control and CPA traces are plotted as in B. D, percentage control peak calcium signal and decay time constants from IS (4, n = 4, FS (□, n = 2)and BT (, n = 2) cell groups. CPA did not significantly reduce peak Ca²⁺ signal but prolonged decays.

Inline graphic — A, two-photon image of an FS cell filled with 200 μM calcium green. Inset shows position of stimulating electrode, S, and position of line scan through two dendrites of interest. B, calcium responses from dendrite 2 (top) and dendrite 1 (bottom) during control stimulation (black) and after addition of 50 μM CPA (grey). Note that the calcium signal was localized to dendrite 1. Decays of calcium transients were fitted to single exponentials as indicated (τ_control = 0.98 s and τ_CPA = 1.48 s). C, calcium transient from B viewed at an expanded time scale, and EPSP (bottom) at same time scale. Control and CPA traces are plotted as in B. D, percentage control peak calcium signal and decay time constants from IS (4, n = 4, FS (□, n = 2)and BT (, n = 2) cell groups. CPA did not significantly reduce peak Ca²⁺ signal but prolonged decays.