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. 2003 Jun 18;551(Pt 1):253–262. doi: 10.1113/jphysiol.2003.046045

Figure 1. Effect of mutant MiRP1 subunits on steady-state activation of HERG.

Figure 1

Steady-state activation (A) and steady-state inactivation (B) curves for HERG alone (▪) and HERG co-expressed with WT (□), T8A (•), Q9E (○) or M54T (▴) MiRP1 subunits. The protocols used to record currents for activation and inactivation are illustrated in the insets (see text for further details). C, summary of the V1/2 of activation (▪) and inactivation (□) for HERG alone and HERG expressed with WT or mutant MiRP1 subunits. Data are means ± S.E.M. (n = 4-7).