Figure 2. Effects of capsaicin on twitch contractions elicited by electrical stimulation (30 μs, 20 V) of the vagus nerve.
A, representative traces showing twitch contractions mediated by vagal stimulation applied every minute, and the effect of capsaicin (3 × 10−5 M for 10 min) on the twitch contractions. The tissue was then washed with PSS for 3 min. After the removal of capsaicin, the twitch contractions recovered to the control level. B, summary plot of the inhibitory effect of capsaicin (3 × 10−7 to 3 × 10−4 M) on twitch contractions. Each data point represents the mean ± S.E.M. of four experiments.