Table 1.

Effect of Y-27632 on the accumulation of inositol phosphates evoked by noradrenaline in aorta and mesenteric artery

	Accumulation of inositol phosphates (% of basal control value)
	Mesenteric artery (n = 8)		Aorta (n = 5)
	Untreated	+Y-27632	Untreated	+Y-27632
Control	100	99 ± 5	100	105.3 ± 4.5
Noradrenaline (0.1 μm)	230 ± 21*	216 ± 16*	343 ± 18*	315 ± 22*
Noradrenaline (1 μM)	395 ± 33*	388 ± 20*	437 ± 19*	411 ± 25*

Artery rings loaded with [³H]myo-inositol were pretreated with or without Y-27632 (10 μm) for 20 min and further incubated with noradrenaline (0.1–1 μm) for 30 min.

^*P < 0.01 vs. control.