Figure 1. Effects of ethanol on spontaneous fluid secretion, secretin-stimulated secretion and ACh-stimulated secretion.

Effects of 1 mM of ethanol on spontaneous fluid secretion (A; n = 5), secretin (0.3 nM)-stimulated secretion (B; n = 6) and ACh (1 μM)-stimulated secretion (C; n = 4) from interlobular duct segments isolated from guinea-pig pancreas superfused with the standard HCO₃⁻ -CO₂ -buffered solution. Values are means ±s.e.m.* Significant differences (P < 0.05) from control levels before the application of ethanol (1 mM).