Figure 2. The CNGB1 subunit of rod CNG channels introduces modulability when co-expressed with the olfactory CNGA2 subunit, which alone does not exhibit modulation.

A, changes in the cGMP sensitivity after patch excision and following ATP application, for homomeric CNGA2 and hybrid CNGA2/CNGB1 channels. B, changes in the channel sensitivity as a result of phosphorylation and dephosphorylation.