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A, effect of application of 750 μM TNP-AMP (AMP), 2000 μM ADP, 15 μM ATP, 15 μM Ap4A and 4 μM oleoyl-CoA on cardiac KATP channels as indicated. B, same concentrations as in A, but with application of 20 μM PIP2 instead of oleoyl-CoA. C, inhibition of KATP channels by (di)adenosine phosphates at the concentrations indicated.
