Skip to main content
. 2003 Sep 5;553(Pt 1):101–112. doi: 10.1113/jphysiol.2003.052845

Figure 9. Proposed interaction of polyamines with the Kir2.1 channel.

Figure 9

A, the molecular structures and dimensions of polyamines. Atom C is plotted in grey and atom N in blue. The dimensions of polyamines were determined by ChemIDPlus (http://chem.sis.nlm.nih.gov/chemidplus/). B, residues 49-98 of one MthK subunit. The colour codes are: blue, A58 (T141); red F87 (D172); green, V91 (I176). The structure is taken from Protein Data Bank (code 1lnq). A spermine molecule is fitted in the pore cavity with the second amine aligned horizontally with F87 (D172). Spd = spermidine, Put = putrescine