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The effects of various blockers on the rates of MTSET modification (s−1 M−1) in the I176C/E224G/E299S mutant
| Ctrl | Spm (1μM) | Spm (1mM) | Spd (1mM) | Put (1mM) | Mg2+(1mM) |
|---|---|---|---|---|---|
| 714.5 ± 67.8 | 595.6 ± 32.5 | 322.7 ± 20.4** | 281.1 ± 6.3*** | 220.4 ± 15.6*** | 307.9 ± 9.6** |
| (n = 5) | (n = 4) | (n = 4) | (n = 4) | (n = 5) | (n = 4) |
Spd, spermidine; Put, putrescine. *P < 0.05
P < 0.005
P < 0.001.
