Figure 4. Developmental changes in AMPA receptor subunit distribution.
GluR-A to -D subunit distribution in hippocampi of wild-type and GluR-A-deficient mice at P14 and P42. Sagittal vibratome brain sections were immunostained with specific antibodies directed against GluR-A, -B, -B/C and -D subunits. Micrograph pictures of the hippocampal subunit distribution visualized by diaminobenzidine (DAB)-labelled secondary antibodies are given (scale bar for 4 upper rows: 1 mm). In the bottom row higher magnification shows putative interneurons positive for the GluR-D subunit (arrows) in the CA1 region. (Scale bar for lower row: 0.13 mm).