Table 3.
Data for cerebral oxygen and glucose uptake () during each of the five protocol periods
Baseline | Pre-hypoxia infusion | Hypoxia | Post-hypoxia infusion | Post-infusion recovery | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Mean | s.e.m. | Mean | s.e.m. | Mean | s.e.m. | Mean | s.e.m. | Mean | s.e.m. | ||
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Control | 100 | – | 110 | 14 | 64 | 10† | 137 | 24 | 132 | 17 |
8-SPT | 100 | – | 125 | 18 | 69 | 7† | 131 | 27 | 9 | ||
DPCPX | 100 | – | 106 | 10 | 87 | 19 | 137 | 37 | 107 | 30 | |
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Control | 100 | – | 109 | 4 | 93 | 8 | 107 | 7 | 127 | 19 |
8-SPT | 100 | – | 120 | 5 | 108 | 13 | 115 | 6 | 172 | 10† | |
DPCPX | 100 | – | 117 | 3 | 111 | 6 | 79 | 8‡ | 122 | 11 |
Cortical uptake of glucose was calculated as the product of cortical flow and the arteriovenous difference.
Significant difference from baseline value (P < 0.05);
significant difference from control for the same time period (P < 0.05).