Table 2.
Aminotransferases 24 h after toxin administration
Mouse strain | AST, units/liter | ALT, units/liter |
---|---|---|
BALB/c WT | 20,476 ± 2,583 | 4,554 ± 726 |
BALB/c SCID | 17,787 ± 3,032 | 4,256 ± 3,762 |
C57BL/6 WT | 26,620 ± 4,841 | 4,667 ± 1,503 |
C57BL/6 SCID | 4,002 ± 916* | 2,225 ± 2,439 |
Liver injury was induced by administration of CCl4 by gavage (3.5 ml/kg, mixed 1:1 with corn oil). Twenty-four hours after gavage, serum aminotransferase levels were measured. WT, wild type; AST, aspartate aminotransferase; ALT, alanine aminotransferase.
P < 0.05 SCID C57BL/6 vs. SCID BALB/c mice (n = 4 for each group).