Table 3.

Serum IgE levels in BALB/c and C57BL/6 wild-type and IFN-γ-deficient mice

Mouse strain	IFN-γ phenotype	Basal (normal)	CCl4
BALB/c	++	0.22  ±  0.03	1.73  ±  0.33*
C57BL/6	++	0.33  ±  0.04	0.98  ±  0.23*†
BALB/c	−−	0.17  ±  0.01	2.60  ±  0.32*‡
C57BL/6	−−	0.15  ±  0.06	1.47  ±  0.48*‡

Units of IgE are mg/nl. Liver injury and fibrosis were as in Table 1. Seven days after the final dose of CCl₄, total serum IgE was quantitated as described. 

^*P < 0.05 compared to basal levels. 

^†P < 0.05 for C57BL/6 IFN-γ^+/+ compared to BALB/c IFN γ^+/+. 

^‡P < 0.05 for BALB/c or C57BL/6^−/− compared to wild-type animals of each strain, respectively (n = 4 for each group).